PT-141 (Bremelanotide)

Research overview

PT-141 (bremelanotide) is a cyclic heptapeptide analog of α-melanocyte-stimulating hormone that acts at melanocortin receptors, with notable affinity for MC4R and MC3R. It is an active pharmaceutical ingredient in an approved prescription product in another context; the material offered here is a research reference standard.

Research use focuses on melanocortin-receptor pharmacology and central nervous system signaling pathways in animal models.

Areas of published research

• Melanocortin receptor binding and selectivity assays
• Central melanocortin signaling in rodent models
• Structure–activity studies of cyclic α-MSH analogs

The list above summarises where this compound appears in the scientific literature. It describes research activity, not properties or effects of any product sold here.

Storage and handling

• Lyophilized vials: store at −20 °C for long-term storage, or 2–8 °C for up to several weeks. Keep sealed and protected from light.
• Allow the vial to reach room temperature before opening, so moisture does not condense on the cold powder.
• After reconstitution with bacteriostatic water, store at 2–8 °C and use within 28 days. Avoid repeated freeze–thaw cycles.
• Add diluent slowly down the inside wall of the vial and swirl gently; do not shake.

Calculate a reconstitution for this vial

Documentation

Each lot is tested by an independent laboratory for purity (RP-HPLC) and identity (mass spectrometry). The certificate of analysis for your lot ships with the order; copies for any lot can be requested through the contact page with the lot number from the vial label. Read our guide on how to read a certificate of analysis.