GHK-Cu

Research overview

GHK-Cu is the copper(II) complex of the naturally occurring tripeptide glycyl-L-histidyl-L-lysine. Plasma levels of the peptide decline with age, which is part of why it has attracted interest in dermatological and regenerative research since the 1970s.

In fibroblast cultures and animal wound models it has been studied for effects on collagen and glycosaminoglycan synthesis, metalloproteinase balance and gene-expression profiles. It is also a common cosmetic ingredient in topical formulations.

Areas of published research

• Fibroblast collagen and elastin synthesis
• Wound-healing and skin-remodeling models
• Hair-follicle growth assays
• Gene-expression modulation studies

The list above summarises where this compound appears in the scientific literature. It describes research activity, not properties or effects of any product sold here.

Storage and handling

• Lyophilized vials: store at −20 °C for long-term storage, or 2–8 °C for up to several weeks. Keep sealed and protected from light.
• Allow the vial to reach room temperature before opening, so moisture does not condense on the cold powder.
• After reconstitution with bacteriostatic water, store at 2–8 °C and use within 28 days. Avoid repeated freeze–thaw cycles.
• Add diluent slowly down the inside wall of the vial and swirl gently; do not shake.

Calculate a reconstitution for this vial

Documentation

Each lot is tested by an independent laboratory for purity (RP-HPLC) and identity (mass spectrometry). The certificate of analysis for your lot ships with the order; copies for any lot can be requested through the contact page with the lot number from the vial label. Read our guide on how to read a certificate of analysis.